Benign Hematology

TRICC trial: Red blood cell transfusion requirements

CHOIR trial: Epoetin alfa and target hemoglobin for CKD

MSH trial: Hydroxyurea for sickle cell anemia

CYTO-PV trial: Hemoglobin target for polycythemia vera

Platelet transfusions for platelet consumptive disorders

IVIG and oral prednisone for ITP

TRAPS trial: Rivoraxaban for antiphospholipid syndrome

PLASMIC score for diagnosis of TTP

Plasma Exchange for TTP

AMPLIFY Trial: Apixaban for VTE

EINSTEIN Trial: Rivaroxaban for VTE



Lo-Coco trial: Retinoic acid + arsenic trioxide for APML

IRIS trial: Imatinib for CML

Ibrutinib-Rituximab for CLL

How Long trial: Antibiotics for febrile neutropenia


ABVD chemotherapy for Hodgkin’s Lymphoma

ECHELON-1 trial: Brentuximab for Hodgkin’s Lymphoma

R-CHOP for non-Hodgkin’s Lymphoma

Plasma Cell Disorders

APEX trial: Bortezomib for Multiple Myeloma

Lenalidomide for Multiple Myeloma

Stem cell transplantation + RVD for Multiple Myeloma

Prognosis of MGUS

Other hematologic disorders

Peripheral blood stem cells for marrow transplant

Lenalidomide for MDS

Do you think there are some important trials we should add to our site? Please contact us at landmarktrials@gmail.com with the trial name, link, and why you think it is a landmark paper!

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