Infectious Disease

COVID – 19

RECOVERY trial: Dexamethasone in COVID-19

ACTT-1 trial: Remdesivir in COVID-19

Pfizer & BioNTech vaccine trial

COVE trial: Moderna vaccine for COVID-19


INSIGHT-START trial: Early initiation of anti-retroviral therapy for HIV

SINGLE trial: Dolutegravir + Abacavir-Lamivudine for HIV

Biktarvy for HIV

iPrEx trial: PREP for HIV prophylaxis

Hepatitis B/C

ION-1 trial: Ledipasvir + sofosbuvir for HCV

VALENCE trial: Sofosbuvir + Ribavirin for HCV

BEHOLD trial: Entecavir + Lamivudine for HCV

Clostridium difficile

Vancomycin and metronidazole for C. diff

Fidaxomicin for C. diff

Fecal transplant for C. diff

Infective Endocarditis

POET trial: Oral vs IV antibiotics for endocarditis

EASE trial: Early surgery for infective endocarditis


Early treatment for sepsis

Dexamethasone for bacterial meningitis

PneumA trial: Duration of antibiotics for VAP

Do you think there are some important trials we should add to our site? Please contact us at with the trial name, link, and why you think it is a landmark paper!

Disclaimer: Please note that articles mentioned on this site are the property of their respective journals. The information from these articles was presented on this site under the Fair Use legal doctrine (Section 107 of the Copyright Act) as the data shared was limited in quantity, factual in nature, already published, and for the purpose of relaying and teaching socially beneficial medical knowledge. The work was attributed to the journals that published them with citations and links provided.